Neuroimaging of motor neuron diseases
نویسندگان
چکیده
منابع مشابه
Motor Neuron Diseases
Although many use the term ‘motor neuron disease’ to refer to amyotrophic lateral sclerosis (ALS), the most common and serious of these disorders occurring in adults, there are a wide variety of different motor neuron diseases, of varying severity, affecting all ages from infancy onwards (Table 1). This death of motor neurons is a form of neurodegenerative disease and results in paralysis of th...
متن کاملEFNS guidelines on the use of neuroimaging in the management of motor neuron diseases.
BACKGROUND AND PURPOSE These European Federation of Neurological Societies guidelines on neuroimaging of motor neuron diseases (MNDs) are designed to provide practical help for the neurologists to make appropriate use of neuroimaging techniques in patients with MNDs, which ranges from diagnostic and monitoring aspects to the in vivo study of the pathobiology of such conditions. METHODS Litera...
متن کاملThe electrophysiology of the motor neuron diseases.
The motor neuron diseases are a set of disorders associated with the selective degeneration of motor neurons. Amyotrophic lateral sclerosis (ALS) is the most common and confers the gravest prognosis. Although ALS occurs with known genetic causes in a small minority, other motor neuron disorders have well-defined genetic mutations. Electrodiagnostic testing is important to distinguish these vari...
متن کاملGene-based treatment of motor neuron diseases.
Motor neuron diseases (MND), such as amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA), are progressive neurodegenerative diseases that share the common characteristic of upper and/or lower motor neuron degeneration. Therapeutic strategies for MND are designed to confer neuroprotection, using trophic factors, anti-apoptotic proteins, as well as antioxidants and anti-excitoto...
متن کاملVitamin B12 deficiency mimicking neuroimaging features of motor neuron disease.
A 45-year-old man presented with 2-month-history of progressive gait disturbances and behavioral changes. Examination showed vibration sense compromise and pyramidal signs of release. Blood test revealed low serum vitamin B12 (120 pg/mL; normal range>200 pg/mL). Brain MRI disclosed hyperintense signal in corticospinal tracts, a similar pattern observed in motor neuron disease (MND) (Figure). Re...
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ژورنال
عنوان ژورنال: Therapeutic Advances in Neurological Disorders
سال: 2012
ISSN: 1756-2864,1756-2864
DOI: 10.1177/1756285612437562